Codelivery of TGF-β1 and anti-miR-141 by PLGA microspheres inhibits progression of intervertebral disc degeneration

BACKGROUND: Cervical and lumbar pain is usually caused by degeneration of the nucleus pulposus (NP). As a powerful therapeutic strategy, tissue engineering can effectively restore the normal biological properties of the spinal unit. Previous studies suggested that poly(lactic-co-glycolic acid) (PLGA...

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Detalles Bibliográficos
Autores principales: Xiao, Liang, Gao, Daokuan, Zhang, Yu, Liu, Chen, Yin, Zongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817358/
https://www.ncbi.nlm.nih.gov/pubmed/36609253
http://dx.doi.org/10.1186/s13018-023-03501-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817358/
https://www.ncbi.nlm.nih.gov/pubmed/36609253
http://dx.doi.org/10.1186/s13018-023-03501-5

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