Pharmacokinetic Basis for Using Saliva Matrine Concentrations as a Clinical Compliance Monitoring in Antitumor B Chemoprevention Trials in Humans

SIMPLE SUMMARY: This is the first human study using saliva samples for drug therapeutic monitoring and patient compliance for a complex botanical extract (e.g., ATB) and reporting the rapid and extensive secretion of certain active compounds (matrine, dictamnine) to human saliva. Specifically, matri...

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Detalles Bibliográficos
Autores principales: Bui, Dinh, McWilliams, Lenora A., Wu, Lei, Zhou, Haiying, Wong, Stuart J., You, Ming, Chow, Diana S.-L., Singh, Rashim, Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817974/
https://www.ncbi.nlm.nih.gov/pubmed/36612086
http://dx.doi.org/10.3390/cancers15010089

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