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Targets, Mechanisms and Cytotoxicity of Half-Sandwich Ir(III) Complexes Are Modulated by Structural Modifications on the Benzazole Ancillary Ligand

SIMPLE SUMMARY: Iridium complexes have been reported as potential drug candidates for the treatment of cancer. They are easy to prepare, and their structure allows several modifications that make them extremely versatile as metallodrugs. Thus, the aim of this work was to get a structure–activity rel...

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Detalles Bibliográficos
Autores principales: Acuña, M. Isabel, Rubio, Ana R., Martínez-Alonso, Marta, Busto, Natalia, Rodríguez, Ana María, Davila-Ferreira, Nerea, Smythe, Carl, Espino, Gustavo, García, Begoña, Domínguez, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818021/
https://www.ncbi.nlm.nih.gov/pubmed/36612104
http://dx.doi.org/10.3390/cancers15010107