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Prevalence of Germline BRCA1/2 Variants in Ashkenazi and Non-Ashkenazi Prostate Cancer Populations: A Systematic Review and Meta-Analysis

SIMPLE SUMMARY: Germline BRCA2 pathogenic variant carriers are associated with prostate cancer risk. Ashkenazi Jewish people are at higher risk of breast cancer due to the high prevalence of specific founder germline BRCA1/2 variants. The distribution of these variants (BRCA1 vs. BRCA2) in Ashkenazi...

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Detalles Bibliográficos
Autores principales: Cioffi, Antonio, De Cobelli, Ottavio, Veronesi, Paolo, La Vecchia, Carlo, Maisonneuve, Patrick, Corso, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818251/
https://www.ncbi.nlm.nih.gov/pubmed/36612302
http://dx.doi.org/10.3390/cancers15010306