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COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx
Background: Early in the pandemic, we established COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx and implemented a detailed evaluation protocol to assess physical, emotional, and cognitive function, pulmonary function tests, and imaging for COVID-19 survivors. Here, we report our findi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818274/ https://www.ncbi.nlm.nih.gov/pubmed/36611411 http://dx.doi.org/10.3390/diagnostics13010119 |
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author | Eligulashvili, Anna Darrell, Megan Miller, Carolyn Lee, Jeylin Congdon, Seth Lee, Jimmy S. Hsu, Kevin Yee, Judy Hou, Wei Islam, Marjan Duong, Tim Q. |
author_facet | Eligulashvili, Anna Darrell, Megan Miller, Carolyn Lee, Jeylin Congdon, Seth Lee, Jimmy S. Hsu, Kevin Yee, Judy Hou, Wei Islam, Marjan Duong, Tim Q. |
author_sort | Eligulashvili, Anna |
collection | PubMed |
description | Background: Early in the pandemic, we established COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx and implemented a detailed evaluation protocol to assess physical, emotional, and cognitive function, pulmonary function tests, and imaging for COVID-19 survivors. Here, we report our findings up to five months post-acute COVID-19. Methods: Main outcomes and measures included pulmonary function tests, imaging tests, and a battery of symptom, physical, emotional, and cognitive assessments 5 months post-acute COVID-19. Findings: Dyspnea, fatigue, decreased exercise tolerance, brain fog, and shortness of breath were the most common symptoms but there were generally no significant differences between hospitalized and non-hospitalized cohorts (p > 0.05). Many patients had abnormal physical, emotional, and cognitive scores, but most functioned independently; there were no significant differences between hospitalized and non-hospitalized cohorts (p > 0.05). Six-minute walk tests, lung ultrasound, and diaphragm excursion were abnormal but only in the hospitalized cohort. Pulmonary function tests showed moderately restrictive pulmonary function only in the hospitalized cohort but no obstructive pulmonary function. Newly detected major neurological events, microvascular disease, atrophy, and white-matter changes were rare, but lung opacity and fibrosis-like findings were common after acute COVID-19. Interpretation: Many COVID-19 survivors experienced moderately restrictive pulmonary function, and significant symptoms across the physical, emotional, and cognitive health domains. Newly detected brain imaging abnormalities were rare, but lung imaging abnormalities were common. This study provides insights into post-acute sequelae following SARS-CoV-2 infection in neurological and pulmonary systems which may be used to support at-risk patients and develop effective screening methods and interventions. |
format | Online Article Text |
id | pubmed-9818274 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98182742023-01-07 COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx Eligulashvili, Anna Darrell, Megan Miller, Carolyn Lee, Jeylin Congdon, Seth Lee, Jimmy S. Hsu, Kevin Yee, Judy Hou, Wei Islam, Marjan Duong, Tim Q. Diagnostics (Basel) Article Background: Early in the pandemic, we established COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx and implemented a detailed evaluation protocol to assess physical, emotional, and cognitive function, pulmonary function tests, and imaging for COVID-19 survivors. Here, we report our findings up to five months post-acute COVID-19. Methods: Main outcomes and measures included pulmonary function tests, imaging tests, and a battery of symptom, physical, emotional, and cognitive assessments 5 months post-acute COVID-19. Findings: Dyspnea, fatigue, decreased exercise tolerance, brain fog, and shortness of breath were the most common symptoms but there were generally no significant differences between hospitalized and non-hospitalized cohorts (p > 0.05). Many patients had abnormal physical, emotional, and cognitive scores, but most functioned independently; there were no significant differences between hospitalized and non-hospitalized cohorts (p > 0.05). Six-minute walk tests, lung ultrasound, and diaphragm excursion were abnormal but only in the hospitalized cohort. Pulmonary function tests showed moderately restrictive pulmonary function only in the hospitalized cohort but no obstructive pulmonary function. Newly detected major neurological events, microvascular disease, atrophy, and white-matter changes were rare, but lung opacity and fibrosis-like findings were common after acute COVID-19. Interpretation: Many COVID-19 survivors experienced moderately restrictive pulmonary function, and significant symptoms across the physical, emotional, and cognitive health domains. Newly detected brain imaging abnormalities were rare, but lung imaging abnormalities were common. This study provides insights into post-acute sequelae following SARS-CoV-2 infection in neurological and pulmonary systems which may be used to support at-risk patients and develop effective screening methods and interventions. MDPI 2022-12-30 /pmc/articles/PMC9818274/ /pubmed/36611411 http://dx.doi.org/10.3390/diagnostics13010119 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Eligulashvili, Anna Darrell, Megan Miller, Carolyn Lee, Jeylin Congdon, Seth Lee, Jimmy S. Hsu, Kevin Yee, Judy Hou, Wei Islam, Marjan Duong, Tim Q. COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title | COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title_full | COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title_fullStr | COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title_full_unstemmed | COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title_short | COVID-19 Patients in the COVID-19 Recovery and Engagement (CORE) Clinics in the Bronx |
title_sort | covid-19 patients in the covid-19 recovery and engagement (core) clinics in the bronx |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818274/ https://www.ncbi.nlm.nih.gov/pubmed/36611411 http://dx.doi.org/10.3390/diagnostics13010119 |
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