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Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review

C-arm systems with digital flat-panel detectors are used in interventional radiology and hybrid operating rooms for visualizing and performing interventions on three-dimensional structures. Advances in C-arm technology have enabled intraoperative quantitative perfusion imaging with these scanners. T...

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Autores principales: Zaid Al-Kaylani, Abdallah H. A., Schuurmann, Richte C. L., Maathuis, Wouter D., Slart, Riemer H. J. A., De Vries, Jean-Paul P. M., Bokkers, Reinoud P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818280/
https://www.ncbi.nlm.nih.gov/pubmed/36611421
http://dx.doi.org/10.3390/diagnostics13010128
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author Zaid Al-Kaylani, Abdallah H. A.
Schuurmann, Richte C. L.
Maathuis, Wouter D.
Slart, Riemer H. J. A.
De Vries, Jean-Paul P. M.
Bokkers, Reinoud P. H.
author_facet Zaid Al-Kaylani, Abdallah H. A.
Schuurmann, Richte C. L.
Maathuis, Wouter D.
Slart, Riemer H. J. A.
De Vries, Jean-Paul P. M.
Bokkers, Reinoud P. H.
author_sort Zaid Al-Kaylani, Abdallah H. A.
collection PubMed
description C-arm systems with digital flat-panel detectors are used in interventional radiology and hybrid operating rooms for visualizing and performing interventions on three-dimensional structures. Advances in C-arm technology have enabled intraoperative quantitative perfusion imaging with these scanners. This systematic review provides an overview of flat-panel detector C-arm techniques for quantifying perfusion, their clinical applications, and their validation. A systematic search was performed for articles published between January 2000 and October 2022 in which a flat-panel detector C-arm technique for quantifying perfusion was compared with a reference technique. Nine articles were retrieved describing two techniques: two-dimensional perfusion angiography (n = 5) and dual-phase cone beam computed tomography perfusion (n = 4). A quality assessment revealed no concerns about the applicability of the studies. The risk of bias was relatively high for the index and reference tests. Both techniques demonstrated potential for clinical application; however, weak-to-moderate correlations were reported between them and the reference techniques. In conclusion, both techniques could add new possibilities to treatment planning and follow-up; however, the available literature is relatively scarce and heterogeneous. Larger-scale randomized prospective studies focusing on clinical outcomes and standardization are required for the full understanding and clinical implementation of these techniques.
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spelling pubmed-98182802023-01-07 Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review Zaid Al-Kaylani, Abdallah H. A. Schuurmann, Richte C. L. Maathuis, Wouter D. Slart, Riemer H. J. A. De Vries, Jean-Paul P. M. Bokkers, Reinoud P. H. Diagnostics (Basel) Systematic Review C-arm systems with digital flat-panel detectors are used in interventional radiology and hybrid operating rooms for visualizing and performing interventions on three-dimensional structures. Advances in C-arm technology have enabled intraoperative quantitative perfusion imaging with these scanners. This systematic review provides an overview of flat-panel detector C-arm techniques for quantifying perfusion, their clinical applications, and their validation. A systematic search was performed for articles published between January 2000 and October 2022 in which a flat-panel detector C-arm technique for quantifying perfusion was compared with a reference technique. Nine articles were retrieved describing two techniques: two-dimensional perfusion angiography (n = 5) and dual-phase cone beam computed tomography perfusion (n = 4). A quality assessment revealed no concerns about the applicability of the studies. The risk of bias was relatively high for the index and reference tests. Both techniques demonstrated potential for clinical application; however, weak-to-moderate correlations were reported between them and the reference techniques. In conclusion, both techniques could add new possibilities to treatment planning and follow-up; however, the available literature is relatively scarce and heterogeneous. Larger-scale randomized prospective studies focusing on clinical outcomes and standardization are required for the full understanding and clinical implementation of these techniques. MDPI 2022-12-30 /pmc/articles/PMC9818280/ /pubmed/36611421 http://dx.doi.org/10.3390/diagnostics13010128 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Zaid Al-Kaylani, Abdallah H. A.
Schuurmann, Richte C. L.
Maathuis, Wouter D.
Slart, Riemer H. J. A.
De Vries, Jean-Paul P. M.
Bokkers, Reinoud P. H.
Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title_full Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title_fullStr Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title_full_unstemmed Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title_short Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review
title_sort clinical applications of quantitative perfusion imaging with a c-arm flat-panel detector—a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818280/
https://www.ncbi.nlm.nih.gov/pubmed/36611421
http://dx.doi.org/10.3390/diagnostics13010128
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