Understanding the Allosteric Modulation of PTH1R by a Negative Allosteric Modulator

The parathyroid hormone type 1 receptor (PTH1R) acts as a canonical class B G protein-coupled receptor, regulating crucial functions including calcium homeostasis and bone formation. The identification and development of PTH1R non-peptide allosteric modulators have obtained widespread attention. It...

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Detalles Bibliográficos
Autores principales: Li, Mengrong, Bao, Yiqiong, Xu, Ran, Li, Miaomiao, Xi, Lili, Guo, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818451/
https://www.ncbi.nlm.nih.gov/pubmed/36611834
http://dx.doi.org/10.3390/cells12010041

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