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Role of Mitochondrial Iron Overload in Mediating Cell Death in H9c2 Cells

Iron overload (IO) is associated with cardiovascular diseases, including heart failure. Our study’s aim was to examine the mechanism by which IO triggers cell death in H9c2 cells. IO caused accumulation of intracellular and mitochondrial iron as shown by the use of iron-binding fluorescent reporters...

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Detalles Bibliográficos
Autores principales: Tam, Eddie, Sung, Hye Kyoung, Lam, Nhat Hung, You, Sally, Cho, Sungji, Ahmed, Saher M., Abdul-Sater, Ali A., Sweeney, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818517/
https://www.ncbi.nlm.nih.gov/pubmed/36611912
http://dx.doi.org/10.3390/cells12010118