Cargando…
A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis
Background: The aim of this study was to compare the choroidal characteristics of typical polypoidal choroidal vasculopathy (T-PCV) and polypoidal choroidal neovascularization (P-CNV) cases, and to investigate the presence of intervortex venous anastomoses in these PCV subtypes by using en face opti...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818584/ https://www.ncbi.nlm.nih.gov/pubmed/36611430 http://dx.doi.org/10.3390/diagnostics13010138 |
_version_ | 1784865021960912896 |
---|---|
author | Batıoğlu, Figen Yanık, Özge Özer, Ferhad Demirel, Sibel Özmert, Emin |
author_facet | Batıoğlu, Figen Yanık, Özge Özer, Ferhad Demirel, Sibel Özmert, Emin |
author_sort | Batıoğlu, Figen |
collection | PubMed |
description | Background: The aim of this study was to compare the choroidal characteristics of typical polypoidal choroidal vasculopathy (T-PCV) and polypoidal choroidal neovascularization (P-CNV) cases, and to investigate the presence of intervortex venous anastomoses in these PCV subtypes by using en face optical coherence tomography angiography (OCTA). Methods: A total of 35 eyes of 33 PCV cases were included. The PCV cases were divided into T-PCV and P-CNV groups. The choroidal vascularity index (CVI) was calculated. En face OCTA images were evaluated for the presence of intervortex venous anastomoses. The diameter of the largest anastomotic Haller vessel was measured. Results: T-PCV cases had significantly higher mean CVI values (73.9 ± 3.7 vs. 70.8 ± 4.5%) than P-CNV cases (p = 0.039). Intervortex venous anastomoses were observed in 85.7% of T-PCV eyes and in 91.7% of P-CNV eyes on en face OCTA (p = 1.000). In the cases with intervortex venous anastomosis, the mean diameter of the largest anastomotic vessel on en face OCTA was 341.2 ± 109.1 µm in the T-PCV and 280.4 ± 68.4 µm in the P-CNV group (p = 0.048). Conclusions: The higher CVI value in T-PCV may be an important feature concerning the pathogenesis and classification of PCV. Although there was no difference between the two subtypes in terms of intervortex anastomosis, more dilated anastomotic vessels were observed in the T-PCV. |
format | Online Article Text |
id | pubmed-9818584 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98185842023-01-07 A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis Batıoğlu, Figen Yanık, Özge Özer, Ferhad Demirel, Sibel Özmert, Emin Diagnostics (Basel) Article Background: The aim of this study was to compare the choroidal characteristics of typical polypoidal choroidal vasculopathy (T-PCV) and polypoidal choroidal neovascularization (P-CNV) cases, and to investigate the presence of intervortex venous anastomoses in these PCV subtypes by using en face optical coherence tomography angiography (OCTA). Methods: A total of 35 eyes of 33 PCV cases were included. The PCV cases were divided into T-PCV and P-CNV groups. The choroidal vascularity index (CVI) was calculated. En face OCTA images were evaluated for the presence of intervortex venous anastomoses. The diameter of the largest anastomotic Haller vessel was measured. Results: T-PCV cases had significantly higher mean CVI values (73.9 ± 3.7 vs. 70.8 ± 4.5%) than P-CNV cases (p = 0.039). Intervortex venous anastomoses were observed in 85.7% of T-PCV eyes and in 91.7% of P-CNV eyes on en face OCTA (p = 1.000). In the cases with intervortex venous anastomosis, the mean diameter of the largest anastomotic vessel on en face OCTA was 341.2 ± 109.1 µm in the T-PCV and 280.4 ± 68.4 µm in the P-CNV group (p = 0.048). Conclusions: The higher CVI value in T-PCV may be an important feature concerning the pathogenesis and classification of PCV. Although there was no difference between the two subtypes in terms of intervortex anastomosis, more dilated anastomotic vessels were observed in the T-PCV. MDPI 2022-12-31 /pmc/articles/PMC9818584/ /pubmed/36611430 http://dx.doi.org/10.3390/diagnostics13010138 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Batıoğlu, Figen Yanık, Özge Özer, Ferhad Demirel, Sibel Özmert, Emin A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title | A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title_full | A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title_fullStr | A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title_full_unstemmed | A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title_short | A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis |
title_sort | comparative study of choroidal vascular and structural characteristics of typical polypoidal choroidal vasculopathy and polypoidal choroidal neovascularization: octa-based evaluation of intervortex venous anastomosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818584/ https://www.ncbi.nlm.nih.gov/pubmed/36611430 http://dx.doi.org/10.3390/diagnostics13010138 |
work_keys_str_mv | AT batıoglufigen acomparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT yanıkozge acomparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT ozerferhad acomparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT demirelsibel acomparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT ozmertemin acomparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT batıoglufigen comparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT yanıkozge comparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT ozerferhad comparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT demirelsibel comparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis AT ozmertemin comparativestudyofchoroidalvascularandstructuralcharacteristicsoftypicalpolypoidalchoroidalvasculopathyandpolypoidalchoroidalneovascularizationoctabasedevaluationofintervortexvenousanastomosis |