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Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice

Doxorubicin (Doxo) is a widely used antineoplastic drug with limited clinical application due to its deleterious dose-related side effects. We investigated whether nicotinamide mononucleotide (NMN) could protect against Doxo-induced cardiotoxicity and physical dysfunction in vivo. To assess the shor...

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Detalles Bibliográficos
Autores principales: Margier, Marielle, Kuehnemann, Chisaka, Hulo, Nicolas, Morales, Jazmin, Ashok Kumaar, Prasanna Vadhana, Cros, Cecile, Cannelle, Helene, Charmetant, Julie, Verdin, Eric, Canault, Matthias, Grozio, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818647/
https://www.ncbi.nlm.nih.gov/pubmed/36611902
http://dx.doi.org/10.3390/cells12010108