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Molecular Basis of HER2-Targeted Therapy for HER2-Positive Colorectal Cancer

SIMPLE SUMMARY: Human epidermal growth factor receptor 2 (HER2) amplification has emerged as a biomarker of metastatic colorectal cancer (mCRC). Prospective clinical trials have demonstrated the efficacy of HER2-targeted therapies for HER2-positive mCRC and explored the underlying mechanisms. To imp...

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Detalles Bibliográficos
Autores principales:	Yoshikawa, Ayumu, Nakamura, Yoshiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818808/ https://www.ncbi.nlm.nih.gov/pubmed/36612185 http://dx.doi.org/10.3390/cancers15010183

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