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Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome
Background: Piriformis syndrome (PS) is a painful musculoskeletal condition characterized by a deep gluteal pain that may radiate to the posterior thigh and leg. This study was designed to compare the effectiveness of ozone and BTX to lidocaine injection in treating piriformis syndrome that was resi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818865/ https://www.ncbi.nlm.nih.gov/pubmed/36611554 http://dx.doi.org/10.3390/healthcare11010095 |
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author | Elsawy, Ahmed Gamal Salah Ameer, Abdulnasir Hussin Gazar, Yasser A. Allam, Abdallah El-Sayed Chan, Shun-Ming Chen, Se-Yi Hou, Jin-De Tai, Yu-Ting Lin, Jui-An Galluccio, Felice Nada, Doaa Waseem Esmat, Ahmed |
author_facet | Elsawy, Ahmed Gamal Salah Ameer, Abdulnasir Hussin Gazar, Yasser A. Allam, Abdallah El-Sayed Chan, Shun-Ming Chen, Se-Yi Hou, Jin-De Tai, Yu-Ting Lin, Jui-An Galluccio, Felice Nada, Doaa Waseem Esmat, Ahmed |
author_sort | Elsawy, Ahmed Gamal Salah |
collection | PubMed |
description | Background: Piriformis syndrome (PS) is a painful musculoskeletal condition characterized by a deep gluteal pain that may radiate to the posterior thigh and leg. This study was designed to compare the effectiveness of ozone and BTX to lidocaine injection in treating piriformis syndrome that was resistant to medication and/or physical therapy. Study design: Between November 2018 and August 2019, we involved eighty-four subjects diagnosed with piriformis syndrome in a double-blinded, prospective, randomized comparative study to receive an ultrasound-guided injection of lidocaine (control group), botulinum toxin A, or local ozone (28 patients each group) in the belly of the piriformis muscle. Pain condition evaluated by the visual analog score (VAS) was used as a primary outcome, and the Oswestry Disability Index (ODI) as a secondary outcome, before, at one month, two months, three months, and six months following the injection. Results: The majority (58.3%) of patients were male, while (41.7%) were female. At one month, a highly significant decrease occurred in VAS and ODI in the lidocaine and ozone groups compared to the botulinum toxin group (p < 0.001). At six months, there was a highly significant decrease in VAS and ODI in the botulinum toxin group compared to the lidocaine and ozone groups (p < 0.001). Conclusion: Botulinum toxin may assist in the medium- and long-term management of piriformis syndrome, while lidocaine injection and ozone therapy may help short-term treatment in patients not responding to conservative treatment and physiotherapy. |
format | Online Article Text |
id | pubmed-9818865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98188652023-01-07 Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome Elsawy, Ahmed Gamal Salah Ameer, Abdulnasir Hussin Gazar, Yasser A. Allam, Abdallah El-Sayed Chan, Shun-Ming Chen, Se-Yi Hou, Jin-De Tai, Yu-Ting Lin, Jui-An Galluccio, Felice Nada, Doaa Waseem Esmat, Ahmed Healthcare (Basel) Article Background: Piriformis syndrome (PS) is a painful musculoskeletal condition characterized by a deep gluteal pain that may radiate to the posterior thigh and leg. This study was designed to compare the effectiveness of ozone and BTX to lidocaine injection in treating piriformis syndrome that was resistant to medication and/or physical therapy. Study design: Between November 2018 and August 2019, we involved eighty-four subjects diagnosed with piriformis syndrome in a double-blinded, prospective, randomized comparative study to receive an ultrasound-guided injection of lidocaine (control group), botulinum toxin A, or local ozone (28 patients each group) in the belly of the piriformis muscle. Pain condition evaluated by the visual analog score (VAS) was used as a primary outcome, and the Oswestry Disability Index (ODI) as a secondary outcome, before, at one month, two months, three months, and six months following the injection. Results: The majority (58.3%) of patients were male, while (41.7%) were female. At one month, a highly significant decrease occurred in VAS and ODI in the lidocaine and ozone groups compared to the botulinum toxin group (p < 0.001). At six months, there was a highly significant decrease in VAS and ODI in the botulinum toxin group compared to the lidocaine and ozone groups (p < 0.001). Conclusion: Botulinum toxin may assist in the medium- and long-term management of piriformis syndrome, while lidocaine injection and ozone therapy may help short-term treatment in patients not responding to conservative treatment and physiotherapy. MDPI 2022-12-28 /pmc/articles/PMC9818865/ /pubmed/36611554 http://dx.doi.org/10.3390/healthcare11010095 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Elsawy, Ahmed Gamal Salah Ameer, Abdulnasir Hussin Gazar, Yasser A. Allam, Abdallah El-Sayed Chan, Shun-Ming Chen, Se-Yi Hou, Jin-De Tai, Yu-Ting Lin, Jui-An Galluccio, Felice Nada, Doaa Waseem Esmat, Ahmed Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title | Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title_full | Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title_fullStr | Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title_full_unstemmed | Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title_short | Efficacy of Ultrasound-Guided Injection of Botulinum Toxin, Ozone, and Lidocaine in Piriformis Syndrome |
title_sort | efficacy of ultrasound-guided injection of botulinum toxin, ozone, and lidocaine in piriformis syndrome |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818865/ https://www.ncbi.nlm.nih.gov/pubmed/36611554 http://dx.doi.org/10.3390/healthcare11010095 |
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