HIV-1 Protease as DNA Immunogen against Drug Resistance in HIV-1 Infection: DNA Immunization with Drug Resistant HIV-1 Protease Protects Mice from Challenge with Protease-Expressing Cells

SIMPLE SUMMARY: DNA immunization with drug-resistant HIV-1 protease (DR PR) is proposed as immunotherapy to prevent the evolution of HIV-1 towards drug resistance and reduce the number of infected cells producing drug-resistant virus. We designed a consensus gene of PR of HIV-1 clade A FSU_A strain...

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Detalles Bibliográficos
Autores principales: Petkov, Stefan, Kilpeläinen, Athina, Bayurova, Ekaterina, Latanova, Anastasia, Mezale, Dzeina, Fridrihsone, Ilse, Starodubova, Elizaveta, Jansons, Juris, Dudorova, Alesja, Gordeychuk, Ilya, Wahren, Britta, Isaguliants, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818955/
https://www.ncbi.nlm.nih.gov/pubmed/36612231
http://dx.doi.org/10.3390/cancers15010238

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