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The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy
Colon capsule endoscopy (CCE) is a promising modality for colonic investigations, but completion rates (CR) and adequate cleansing rates (ACR) must be improved to meet established standards for optical colonoscopy. Improvements should be made with patient acceptability in mind. We aimed to compare a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818960/ https://www.ncbi.nlm.nih.gov/pubmed/36611310 http://dx.doi.org/10.3390/diagnostics13010018 |
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author | Schelde-Olesen, Benedicte Nemeth, Artur Johansson, Gabriele Wurm Deding, Ulrik Bjørsum-Meyer, Thomas Thorlacius, Henrik Baatrup, Gunnar Koulaouzidis, Anastasios Toth, Ervin |
author_facet | Schelde-Olesen, Benedicte Nemeth, Artur Johansson, Gabriele Wurm Deding, Ulrik Bjørsum-Meyer, Thomas Thorlacius, Henrik Baatrup, Gunnar Koulaouzidis, Anastasios Toth, Ervin |
author_sort | Schelde-Olesen, Benedicte |
collection | PubMed |
description | Colon capsule endoscopy (CCE) is a promising modality for colonic investigations, but completion rates (CR) and adequate cleansing rates (ACR) must be improved to meet established standards for optical colonoscopy. Improvements should be made with patient acceptability in mind. We aimed to compare a very low-volume polyethylene glycol (PEG) laxative to a conventional high-volume laxative. We carried out a single-center retrospective comparative cohort study including patients referred for CCE. One hundred and sixty-six patients were included in the final analysis, with eighty-three patients in each group. We found a CR and ACR of 77% and 67% in the high-volume group and 72% and 75% in the very low-volume group, respectively. In the high-volume group, 54% had complete transit and adequate cleansing, whereas this was the case for 63% in the very low-volume group. No statistically significant difference in CR, ACR, or a combination of the two was found. A very low-volume bowel preparation regimen was non-inferior to a high-volume regimen before CCE in terms of CR and ACR. |
format | Online Article Text |
id | pubmed-9818960 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98189602023-01-07 The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy Schelde-Olesen, Benedicte Nemeth, Artur Johansson, Gabriele Wurm Deding, Ulrik Bjørsum-Meyer, Thomas Thorlacius, Henrik Baatrup, Gunnar Koulaouzidis, Anastasios Toth, Ervin Diagnostics (Basel) Article Colon capsule endoscopy (CCE) is a promising modality for colonic investigations, but completion rates (CR) and adequate cleansing rates (ACR) must be improved to meet established standards for optical colonoscopy. Improvements should be made with patient acceptability in mind. We aimed to compare a very low-volume polyethylene glycol (PEG) laxative to a conventional high-volume laxative. We carried out a single-center retrospective comparative cohort study including patients referred for CCE. One hundred and sixty-six patients were included in the final analysis, with eighty-three patients in each group. We found a CR and ACR of 77% and 67% in the high-volume group and 72% and 75% in the very low-volume group, respectively. In the high-volume group, 54% had complete transit and adequate cleansing, whereas this was the case for 63% in the very low-volume group. No statistically significant difference in CR, ACR, or a combination of the two was found. A very low-volume bowel preparation regimen was non-inferior to a high-volume regimen before CCE in terms of CR and ACR. MDPI 2022-12-21 /pmc/articles/PMC9818960/ /pubmed/36611310 http://dx.doi.org/10.3390/diagnostics13010018 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schelde-Olesen, Benedicte Nemeth, Artur Johansson, Gabriele Wurm Deding, Ulrik Bjørsum-Meyer, Thomas Thorlacius, Henrik Baatrup, Gunnar Koulaouzidis, Anastasios Toth, Ervin The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title | The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title_full | The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title_fullStr | The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title_full_unstemmed | The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title_short | The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy |
title_sort | effectiveness of a very low-volume compared to high-volume laxative in colon capsule endoscopy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818960/ https://www.ncbi.nlm.nih.gov/pubmed/36611310 http://dx.doi.org/10.3390/diagnostics13010018 |
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