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Potent and Targeted Sindbis Virus Platform for Immunotherapy of Ovarian Cancer

Our laboratory has been developing a Sindbis viral (SV) vector platform for treatments of ovarian and other types of cancers. In this study we show that SV.IL-12 combined with an agonistic OX40 antibody can eliminate ovarian cancer in a Mouse Ovarian Surface Epithelial Cell Line (MOSEC) model and fu...

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Detalles Bibliográficos
Autores principales: Opp, Silvana, Hurtado, Alicia, Pampeno, Christine, Lin, Ziyan, Meruelo, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818975/
https://www.ncbi.nlm.nih.gov/pubmed/36611875
http://dx.doi.org/10.3390/cells12010077

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