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Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model

The COVID-19 pandemic has revealed new features in terms of substantial changes in rates of infection, cure, and death as a result of social interventions, which significantly challenges traditional SEIR-type models. In this paper we developed a symmetry-based model for quantifying social interventi...

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Autores principales: Zhang, Lei, She, Guang-Hui, She, Yu-Rong, Li, Rong, She, Zhen-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9819631/
https://www.ncbi.nlm.nih.gov/pubmed/36612798
http://dx.doi.org/10.3390/ijerph20010476
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author Zhang, Lei
She, Guang-Hui
She, Yu-Rong
Li, Rong
She, Zhen-Su
author_facet Zhang, Lei
She, Guang-Hui
She, Yu-Rong
Li, Rong
She, Zhen-Su
author_sort Zhang, Lei
collection PubMed
description The COVID-19 pandemic has revealed new features in terms of substantial changes in rates of infection, cure, and death as a result of social interventions, which significantly challenges traditional SEIR-type models. In this paper we developed a symmetry-based model for quantifying social interventions for combating COVID-19. We found that three key order parameters, separating degree ([Formula: see text]) for susceptible populations, healing degree ([Formula: see text]) for mild cases, and rescuing degree ([Formula: see text]) for severe cases, all display logistic dynamics, establishing a novel dynamic model named SHR. Furthermore, we discovered two evolutionary patterns of healing degree with a universal power law in 23 areas in the first wave. Remarkably, the model yielded a quantitative evaluation of the dynamic back-to-zero policy in the third wave in Beijing using 12 datasets of different sizes. In conclusion, the SHR model constitutes a rational basis by which we can understand this complex epidemic and policymakers can carry out sustainable anti-epidemic measures to minimize its impact.
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spelling pubmed-98196312023-01-07 Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model Zhang, Lei She, Guang-Hui She, Yu-Rong Li, Rong She, Zhen-Su Int J Environ Res Public Health Article The COVID-19 pandemic has revealed new features in terms of substantial changes in rates of infection, cure, and death as a result of social interventions, which significantly challenges traditional SEIR-type models. In this paper we developed a symmetry-based model for quantifying social interventions for combating COVID-19. We found that three key order parameters, separating degree ([Formula: see text]) for susceptible populations, healing degree ([Formula: see text]) for mild cases, and rescuing degree ([Formula: see text]) for severe cases, all display logistic dynamics, establishing a novel dynamic model named SHR. Furthermore, we discovered two evolutionary patterns of healing degree with a universal power law in 23 areas in the first wave. Remarkably, the model yielded a quantitative evaluation of the dynamic back-to-zero policy in the third wave in Beijing using 12 datasets of different sizes. In conclusion, the SHR model constitutes a rational basis by which we can understand this complex epidemic and policymakers can carry out sustainable anti-epidemic measures to minimize its impact. MDPI 2022-12-28 /pmc/articles/PMC9819631/ /pubmed/36612798 http://dx.doi.org/10.3390/ijerph20010476 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Lei
She, Guang-Hui
She, Yu-Rong
Li, Rong
She, Zhen-Su
Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title_full Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title_fullStr Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title_full_unstemmed Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title_short Quantifying Social Interventions for Combating COVID-19 via a Symmetry-Based Model
title_sort quantifying social interventions for combating covid-19 via a symmetry-based model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9819631/
https://www.ncbi.nlm.nih.gov/pubmed/36612798
http://dx.doi.org/10.3390/ijerph20010476
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