Cargando…

Hippocampal Deletion of CB1 Receptor Impairs Social Memory and Leads to Age-Related Changes in the Hippocampus of Adult Mice

Endocannabinoid system activity declines with age in the hippocampus, along with the density of the cannabinoid receptor type-1 (CB1). This process might contribute to brain ageing, as previous studies showed that the constitutive deletion of the CB1 receptor in mice leads to early onset of memory d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palmisano, Michela, Gargano, Alessandra, Olabiyi, Bolanle Fatimat, Lutz, Beat, Bilkei-Gorzo, Andras
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9819823/ https://www.ncbi.nlm.nih.gov/pubmed/36613469 http://dx.doi.org/10.3390/ijms24010026

Ejemplares similares

Possible role of locus coeruleus neuronal loss in age-related memory and attention deficits
por: Gargano, Alessandra, et al.
Publicado: (2023)

Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory
por: Albayram, Onder, et al.
Publicado: (2012)

Lack of Cannabinoid Receptor Type-1 Leads to Enhanced Age-Related Neuronal Loss in the Locus Coeruleus
por: Gargano, Alessandra, et al.
Publicado: (2020)

Involvement of leptin signaling in the development of cannabinoid CB2 receptor-dependent mirror image pain
por: Nozaki, Chihiro, et al.
Publicado: (2018)

Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor
por: Pascual Cuadrado, Diego, et al.
Publicado: (2021)

Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner
por: Komorowska-Müller, Joanna Agnieszka, et al.
Publicado: (2021)

Efficacy of Δ(9) -Tetrahydrocannabinol (THC) Alone or in Combination With a 1:1 Ratio of Cannabidiol (CBD) in Reversing the Spatial Learning Deficits in Old Mice
por: Nidadavolu, Prakash, et al.
Publicado: (2021)

Author Correction: Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation
por: Olabiyi, Bolanle Fatimat, et al.
Publicado: (2023)

Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation
por: Olabiyi, Bolanle Fatimat, et al.
Publicado: (2023)

Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity
por: Ativie, Frank, et al.
Publicado: (2018)

Hippocampal CB(1) receptors mediate the memory impairing effects of Δ(9)-tetrahydrocannabinol
por: Wise, Laura E., et al.
Publicado: (2009)

proNGF Involvement in the Adult Neurogenesis Dysfunction in Alzheimer’s Disease
por: Olabiyi, Bolanle Fatimat, et al.
Publicado: (2021)

Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis
por: Nidadavolu, Prakash, et al.
Publicado: (2022)

AAV Vector-Mediated Overexpression of CB1 Cannabinoid Receptor in Pyramidal Neurons of the Hippocampus Protects against Seizure-Induced Excitoxicity
por: Guggenhuber, Stephan, et al.
Publicado: (2010)

Developmental programming of somatic growth, behavior and endocannabinoid metabolism by variation of early postnatal nutrition in a cross-fostering mouse model
por: Schreiner, Felix, et al.
Publicado: (2017)

Modulation of feeding behavior and metabolism by dynorphin
por: Ghule, Aishwarya, et al.
Publicado: (2020)

Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity
por: Srivastava, Raj Kamal, et al.
Publicado: (2022)

Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa)
por: Schuele, Lena-Louise, et al.
Publicado: (2022)

Enhance, delete, incept: Manipulating hippocampus-dependent memories()
por: Spiers, Hugo J., et al.
Publicado: (2014)

Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain
por: Bilkei-Gorzo, Andras, et al.
Publicado: (2018)

Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus
por: Lee, Jonathan L. C., et al.
Publicado: (2019)

Macrophages and scavenger receptors in obesity‐associated non‐alcoholic liver fatty disease (NAFLD)
por: Kragh Petersen, Sine, et al.
Publicado: (2020)

Chronic low-dose Δ(9)-tetrahydrocannabinol (THC) treatment stabilizes dendritic spines in 18-month-old mice
por: Komorowska-Müller, Joanna Agnieszka, et al.
Publicado: (2023)

Aging and the Combined effects of ADRA2B and CB1 deletions on Affective Working Memory
por: Fairfield, Beth, et al.
Publicado: (2019)

Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior
por: Cherix, Antoine, et al.
Publicado: (2022)

Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome
por: Hansen, Katelin F., et al.
Publicado: (2016)

Cannabinoid receptor 2 deletion influences social memory and synaptic architecture in the hippocampus
por: Komorowska-Müller, Joanna Agnieszka, et al.
Publicado: (2021)

Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory
por: Kong, Qingnuan, et al.
Publicado: (2020)

Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior
por: Otte, David-Marian, et al.
Publicado: (2013)

Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity
por: Miranda, Kathryn, et al.
Publicado: (2022)

Circuit Specific Functions of Cannabinoid CB1 Receptor in the Balance of Investigatory Drive and Exploration
por: Häring, Martin, et al.
Publicado: (2011)

SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice
por: Ang, Mary Jasmin, et al.
Publicado: (2021)

Age-Related Memory Impairment Is Associated with Disrupted Multivariate Epigenetic Coordination in the Hippocampus
por: Castellano, James F., et al.
Publicado: (2012)

Effect of Recombinant Insulin-like Growth Factor-2 Injected into the Hippocampus on Memory Impairment Following Hippocampal Intracerebral Hemorrhage in Rats
por: Vafaee, Farzaneh, et al.
Publicado: (2018)

AhR Deletion Promotes Aberrant Morphogenesis and Synaptic Activity of Adult-Generated Granule Neurons and Impairs Hippocampus-Dependent Memory
por: de la Parra, Juan, et al.
Publicado: (2018)

Effects of drugs of abuse on hippocampal plasticity and hippocampus-dependent learning and memory: contributions to development and maintenance of addiction
por: Kutlu, Munir Gunes, et al.
Publicado: (2016)

Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice
por: Cheng, Li, et al.
Publicado: (2022)

Stable Adult Hippocampal Neurogenesis in Cannabinoid Receptor CB2 Deficient Mice
por: Mensching, Leonore, et al.
Publicado: (2019)

Lung macrophages utilize unique cathepsin K–dependent phagosomal machinery to degrade intracellular collagen
por: Fabrik, Ivo, et al.
Publicado: (2023)

Hippocampus-dependent learning influences hippocampal neurogenesis
por: Epp, Jonathan R., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ee8dkmb0ei2dakrbh43du58vas