Synthesis of 9-Hydroxy-1H-Benzo[f]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P-Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis Effects

β-Enaminonitriles bearing 9-hydroxy-1H-benzo[f]chromene moiety was synthesized. The targeted compounds were evaluated for their anti-proliferative activity against three human tumor cell lines, PC-3, SKOV-3 and HeLa, and the active cytotoxic compounds were further evaluated against cancer cells, MCF...

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Detalles Bibliográficos
Autores principales: Albalawi, Fawzia F., El-Nassag, Mohammed A. A., El-Eisawy, Raafat A., Mohamed, Mahmoud Basseem I., Fouda, Ahmed M., Afifi, Tarek H., Elhenawy, Ahmed A., Mora, Ahmed, El-Agrody, Ahmed M., El-Mawgoud, Heba K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820082/
https://www.ncbi.nlm.nih.gov/pubmed/36613493
http://dx.doi.org/10.3390/ijms24010049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820082/
https://www.ncbi.nlm.nih.gov/pubmed/36613493
http://dx.doi.org/10.3390/ijms24010049

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