Grading of Aortic Stenosis: Is it More Complicated in Women?
Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Radcliffe Cardiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820123/ https://www.ncbi.nlm.nih.gov/pubmed/36643071 http://dx.doi.org/10.15420/ecr.2022.13 |
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author | Cramariuc, Dana Bahlmann, Edda Gerdts, Eva |
author_facet | Cramariuc, Dana Bahlmann, Edda Gerdts, Eva |
author_sort | Cramariuc, Dana |
collection | PubMed |
description | Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed. |
format | Online Article Text |
id | pubmed-9820123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Radcliffe Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-98201232023-01-12 Grading of Aortic Stenosis: Is it More Complicated in Women? Cramariuc, Dana Bahlmann, Edda Gerdts, Eva Eur Cardiol SF on Sex Differences in AVS Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed. Radcliffe Cardiology 2022-11-01 /pmc/articles/PMC9820123/ /pubmed/36643071 http://dx.doi.org/10.15420/ecr.2022.13 Text en Copyright © 2022, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly. |
spellingShingle | SF on Sex Differences in AVS Cramariuc, Dana Bahlmann, Edda Gerdts, Eva Grading of Aortic Stenosis: Is it More Complicated in Women? |
title | Grading of Aortic Stenosis: Is it More Complicated in Women? |
title_full | Grading of Aortic Stenosis: Is it More Complicated in Women? |
title_fullStr | Grading of Aortic Stenosis: Is it More Complicated in Women? |
title_full_unstemmed | Grading of Aortic Stenosis: Is it More Complicated in Women? |
title_short | Grading of Aortic Stenosis: Is it More Complicated in Women? |
title_sort | grading of aortic stenosis: is it more complicated in women? |
topic | SF on Sex Differences in AVS |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820123/ https://www.ncbi.nlm.nih.gov/pubmed/36643071 http://dx.doi.org/10.15420/ecr.2022.13 |
work_keys_str_mv | AT cramariucdana gradingofaorticstenosisisitmorecomplicatedinwomen AT bahlmannedda gradingofaorticstenosisisitmorecomplicatedinwomen AT gerdtseva gradingofaorticstenosisisitmorecomplicatedinwomen |