Grading of Aortic Stenosis: Is it More Complicated in Women?

Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity...

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Autores principales: Cramariuc, Dana, Bahlmann, Edda, Gerdts, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820123/
https://www.ncbi.nlm.nih.gov/pubmed/36643071
http://dx.doi.org/10.15420/ecr.2022.13
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author Cramariuc, Dana
Bahlmann, Edda
Gerdts, Eva
author_facet Cramariuc, Dana
Bahlmann, Edda
Gerdts, Eva
author_sort Cramariuc, Dana
collection PubMed
description Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed.
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spelling pubmed-98201232023-01-12 Grading of Aortic Stenosis: Is it More Complicated in Women? Cramariuc, Dana Bahlmann, Edda Gerdts, Eva Eur Cardiol SF on Sex Differences in AVS Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and transcatheter aortic valve replacement. Women and men have different AS severity grades at the same level of aortic valve calcification. Moreover, besides having smaller cardiac volumes, left ventricular outflow tract and aortic size, women have a specific pattern of left ventricular structural and functional remodelling in response to the AS-related chronic pressure overload. Here, the sex-specific cardiac changes in AS that make AS grading more challenging in women, with consequences for the management and outcome of this group of patients, are reviewed. Radcliffe Cardiology 2022-11-01 /pmc/articles/PMC9820123/ /pubmed/36643071 http://dx.doi.org/10.15420/ecr.2022.13 Text en Copyright © 2022, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle SF on Sex Differences in AVS
Cramariuc, Dana
Bahlmann, Edda
Gerdts, Eva
Grading of Aortic Stenosis: Is it More Complicated in Women?
title Grading of Aortic Stenosis: Is it More Complicated in Women?
title_full Grading of Aortic Stenosis: Is it More Complicated in Women?
title_fullStr Grading of Aortic Stenosis: Is it More Complicated in Women?
title_full_unstemmed Grading of Aortic Stenosis: Is it More Complicated in Women?
title_short Grading of Aortic Stenosis: Is it More Complicated in Women?
title_sort grading of aortic stenosis: is it more complicated in women?
topic SF on Sex Differences in AVS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820123/
https://www.ncbi.nlm.nih.gov/pubmed/36643071
http://dx.doi.org/10.15420/ecr.2022.13
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