Inactivation of PTEN and ZFHX3 in Mammary Epithelial Cells Alters Patterns of Collective Cell Migration

Whole exome sequencing of invasive mammary carcinomas revealed the association of mutations in PTEN and ZFHX3 tumor suppressor genes (TSGs). We generated single and combined PTEN and ZFHX3 knock-outs (KOs) in the immortalized mammary epithelial cell line MCF10A to study the role of these genes and t...

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Detalles Bibliográficos
Autores principales: Dayoub, Ali, Fokin, Artem I., Lomakina, Maria E., James, John, Plays, Marina, Jacquin, Tom, Novikov, Nikita M., Vorobyov, Rostislav S., Schegoleva, Anastasia A., Rysenkova, Karina D., Gaboriaud, Julia, Leonov, Sergey V., Denisov, Evgeny V., Gautreau, Alexis M., Alexandrova, Antonina Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820126/
https://www.ncbi.nlm.nih.gov/pubmed/36613756
http://dx.doi.org/10.3390/ijms24010313

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