CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene setd5 Leads to Social Impairments in Zebrafish

Haploinsufficiency of the SETD5 gene, encoding a SET domain-containing histone methyltransferase, has been identified as a cause of intellectual disability and Autism Spectrum Disorder (ASD). Recently, the zebrafish has emerged as a valuable model to study neurodevelopmental disorders because of its...

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Detalles Bibliográficos
Autores principales: Gabellini, Chiara, Pucci, Cecilia, De Cesari, Chiara, Martini, Davide, Di Lauro, Caterina, Digregorio, Matteo, Norton, William, Zippo, Alessio, Sessa, Alessandro, Broccoli, Vania, Andreazzoli, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820161/
https://www.ncbi.nlm.nih.gov/pubmed/36613611
http://dx.doi.org/10.3390/ijms24010167

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