Optogenetic Low-Frequency Stimulation of Principal Neurons, but Not Parvalbumin-Positive Interneurons, Prevents Generation of Ictal Discharges in Rodent Entorhinal Cortex in an In Vitro 4-Aminopyridine Model

Low-frequency electrical stimulation is used to treat some drug-resistant forms of epilepsy. Despite the effectiveness of the method in suppressing seizures, there is a considerable risk of side effects. An optogenetic approach allows the targeting of specific populations of neurons, which can incre...

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Detalles Bibliográficos
Autores principales: Proskurina, Elena Y., Chizhov, Anton V., Zaitsev, Aleksey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820186/
https://www.ncbi.nlm.nih.gov/pubmed/36613660
http://dx.doi.org/10.3390/ijms24010195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820186/
https://www.ncbi.nlm.nih.gov/pubmed/36613660
http://dx.doi.org/10.3390/ijms24010195

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