Increasing Stress to Induce Apoptosis in Pancreatic Cancer via the Unfolded Protein Response (UPR)

High rates of cell proliferation and protein synthesis in pancreatic cancer are among many factors leading to endoplasmic reticulum (ER) stress. To restore cellular homeostasis, the unfolded protein response (UPR) activates as an adaptive mechanism through either the IRE1 [Formula: see text] , PERK,...

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Detalles Bibliográficos
Autores principales: Botrus, Gehan, Miller, Richard M., Uson Junior, Pedro Luiz Serrano, Kannan, Geoffrey, Han, Haiyong, Von Hoff, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820188/
https://www.ncbi.nlm.nih.gov/pubmed/36614019
http://dx.doi.org/10.3390/ijms24010577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820188/
https://www.ncbi.nlm.nih.gov/pubmed/36614019
http://dx.doi.org/10.3390/ijms24010577

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