A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants

We performed a genome-wide association study (GWAS) of human extreme longevity (EL), defined as surviving past the 99th survival percentile, by aggregating data from four centenarian studies. The combined data included 2304 EL cases and 5879 controls. The analysis identified a locus in CDKN2B-AS1 (r...

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Detalles Bibliográficos
Autores principales: Bae, Harold, Gurinovich, Anastasia, Karagiannis, Tanya T., Song, Zeyuan, Leshchyk, Anastasia, Li, Mengze, Andersen, Stacy L., Arbeev, Konstantin, Yashin, Anatoliy, Zmuda, Joseph, An, Ping, Feitosa, Mary, Giuliani, Cristina, Franceschi, Claudio, Garagnani, Paolo, Mengel-From, Jonas, Atzmon, Gil, Barzilai, Nir, Puca, Annibale, Schork, Nicholas J., Perls, Thomas T., Sebastiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820206/
https://www.ncbi.nlm.nih.gov/pubmed/36613555
http://dx.doi.org/10.3390/ijms24010116

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