TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation

Myocardial damage caused by the newly emerged coronavirus (SARS-CoV-2) infection is one of the key determinants of COVID-19 severity and mortality. SARS-CoV-2 entry to host cells is initiated by binding with its receptor, angiotensin-converting enzyme (ACE) 2, and the ACE2 abundance is thought to re...

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Detalles Bibliográficos
Autores principales: Kato, Yuri, Nishiyama, Kazuhiro, Man Lee, Jae, Ibuki, Yuko, Imai, Yumiko, Noda, Takamasa, Kamiya, Noriho, Kusakabe, Takahiro, Kanda, Yasunari, Nishida, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820218/
https://www.ncbi.nlm.nih.gov/pubmed/36613540
http://dx.doi.org/10.3390/ijms24010102

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