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Role of Adenylyl Cyclase Type 7 in Functions of BV-2 Microglia

To assess the role of adenylyl cyclase type 7 (AC7) in microglia’s immune function, we generated AC7 gene knockout (AC7 KO) clones from a mouse microglial cell line, BV-2, using the CRISPR-Cas9 gene editing system. The ability of BV-2 cells to generate cAMP and their innate immune functions were exa...

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Detalles Bibliográficos
Autores principales:	Hu, Yawen, Hill, Rebecca A., Yoshimura, Masami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820266/ https://www.ncbi.nlm.nih.gov/pubmed/36613790 http://dx.doi.org/10.3390/ijms24010347

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