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The Role of ER Stress in Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome
The endoplasmic reticulum (ER) is a cytosolic organelle that plays an essential role in the folding and processing of new secretory proteins, including insulin. The pathogenesis of diabetes, a group of metabolic disorders caused by dysfunctional insulin secretion (Type 1 diabetes, T1DM) or insulin s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820298/ https://www.ncbi.nlm.nih.gov/pubmed/36613674 http://dx.doi.org/10.3390/ijms24010230 |