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Intraperitoneally Delivered Umbilical Cord Lining Mesenchymal Stromal Cells Improve Survival and Kidney Function in Murine Lupus via Myeloid Pathway Targeting

To determine the therapeutic efficacy of human umbilical cord lining mesenchymal stromal cells (CL-MSCs) (US Patent number 9,737,568) in lupus-prone MRL/lpr (Fas(lpr)) mice and elucidate its working mechanisms. A total of 4 doses of (20–25) × 10(6) cells/kg of CL-MSCs was given to 16-week-old female...

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Detalles Bibliográficos
Autores principales:	Chua, Alvin Wen Choong, Guo, Dianyang, Tan, Jia Chi, Lim, Frances Ting Wei, Ong, Chee Tian, Masilamani, Jeyakumar, Lim, Tony Kiat Hon, Hwang, William Ying Khee, Lim, Ivor Jiun, Chen, Jinmiao, Phan, Toan Thang, Fan, Xiubo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820333/ https://www.ncbi.nlm.nih.gov/pubmed/36613807 http://dx.doi.org/10.3390/ijms24010365

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