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Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats

Oxidative stress, neurodegeneration, neuroinflammation, and vascular leakage are believed to play a key role in the early stage of diabetic retinopathy (ESDR). The aim of this study was to investigate the blockade of cannabinoid receptor 1 (CB1R) and activation of cannabinoid receptor 2 (CB2R) as pu...

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Detalles Bibliográficos
Autores principales: Spyridakos, Dimitris, Mastrodimou, Niki, Vemuri, Kiran, Ho, Thanh C., Nikas, Spyros P., Makriyannis, Alexandros, Thermos, Kyriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820336/
https://www.ncbi.nlm.nih.gov/pubmed/36613692
http://dx.doi.org/10.3390/ijms24010240

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