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The Apparent Organ-Specificity of Amyloidogenic ApoA-I Variants Is Linked to Tissue-Specific Extracellular Matrix Components

Apolipoprotein A-I (ApoA-I) amyloidosis is a rare protein misfolding disease where fibrils of the N-terminal domain of the protein accumulate in several organs, leading to their failure. Although ApoA-I amyloidosis is systemic, the different amyloidogenic variants show a preferential tissue accumula...

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Detalles Bibliográficos
Autores principales:	Del Giudice, Rita, Lindvall, Mikaela, Nilsson, Oktawia, Monti, Daria Maria, Lagerstedt, Jens O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820410/ https://www.ncbi.nlm.nih.gov/pubmed/36613763 http://dx.doi.org/10.3390/ijms24010318

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