Evidence for a Conserved Function of Eukaryotic Pantothenate Kinases in the Regulation of Mitochondrial Homeostasis and Oxidative Stress

Human PANK1, PANK2, and PANK3 genes encode several pantothenate kinase isoforms that catalyze the phosphorylation of vitamin B5 (pantothenic acid) to phosphopantothenate, a critical step in the biosynthesis of the major cellular cofactor, Coenzyme A (CoA). Mutations in the PANK2 gene, which encodes...

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Detalles Bibliográficos
Autores principales: Ceccatelli Berti, Camilla, Gihaz, Shalev, Figuccia, Sonia, Choi, Jae-Yeon, Pal, Anasuya C., Goffrini, Paola, Ben Mamoun, Choukri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820505/
https://www.ncbi.nlm.nih.gov/pubmed/36613877
http://dx.doi.org/10.3390/ijms24010435

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