Cargando…

Bempedoic Acid Restores Liver H(2)S Production in a Female Sprague-Dawley Rat Dietary Model of Non-Alcoholic Fatty Liver

We previously demonstrated that treatment with BemA (bempedoic acid), an inhibitor of ATP citrate lyase, significantly reduces fatty liver in a model of liver steatosis (HFHFr—female Sprague-Dawley rat fed a high-fat high-fructose diet). Since the hepatic production of the gasotransmitter H(2)S is i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roglans, Núria, Fauste, Elena, Bentanachs, Roger, Velázquez, Ana M., Pérez-Armas, Madelin, Donis, Cristina, Panadero, María I., Alegret, Marta, Otero, Paola, Bocos, Carlos, Laguna, Juan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820553/ https://www.ncbi.nlm.nih.gov/pubmed/36613916 http://dx.doi.org/10.3390/ijms24010473

Ejemplares similares

KHK, PNPLA3 and PPAR as Novel Targets for the Anti-Steatotic Action of Bempedoic Acid
por: Velázquez, Ana Magdalena, et al.
Publicado: (2022)

Chronic liquid fructose supplementation does not cause liver tumorigenesis but elicits clear sex differences in the metabolic response in Sprague–Dawley rats
por: Roglans, Nuria, et al.
Publicado: (2021)

Maternal fructose boosts the effects of a Western-type diet increasing SARS-COV-2 cell entry factors in male offspring
por: Fauste, Elena, et al.
Publicado: (2023)

Pregnancy Is Enough to Provoke Deleterious Effects in Descendants of Fructose-Fed Mothers and Their Fetuses
por: Fauste, Elena, et al.
Publicado: (2021)

ChREBP‐driven DNL and PNPLA3 Expression Induced by Liquid Fructose are Essential in the Production of Fatty Liver and Hypertriglyceridemia in a High‐Fat Diet‐Fed Rat Model
por: Velázquez, Ana Magdalena, et al.
Publicado: (2022)

Effects of Maternal Fructose Intake on Perinatal ER-Stress: A Defective XBP1s Nuclear Translocation Affects the ER-stress Resolution
por: Rodrigo, Silvia, et al.
Publicado: (2019)

Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation
por: Velázquez, Ana Magdalena, et al.
Publicado: (2020)

Maternal fructose intake reinforces the effects of a Western-type diet in promoting SARS-CoV-2 cell entry factors in male offspring
por: Donis, C., et al.
Publicado: (2022)

Simple Sugar Intake and Hepatocellular Carcinoma: Epidemiological and Mechanistic Insight
por: Laguna, Juan Carlos, et al.
Publicado: (2014)

Metabolic Alterations and Increased Liver mTOR Expression Precede the Development of Autoimmune Disease in a Murine Model of Lupus Erythematosus
por: Vilà, Laia, et al.
Publicado: (2012)

Adipose Tissue Protects against Hepatic Steatosis in Male Rats Fed a High-Fat Diet plus Liquid Fructose: Sex-Related Differences
por: Bentanachs, Roger, et al.
Publicado: (2023)

mTOR is a Key Protein Involved in the Metabolic Effects of Simple Sugars
por: Sangüesa, Gemma, et al.
Publicado: (2019)

Study on the Pathogenesis of Foreign Body Granulomatous Inflammation in the Livers of Sprague-Dawley Rats
por: Shiga, Atsushi, et al.
Publicado: (2010)

Oral contraceptive steroids as promoters or complete carcinogens for liver in female Sprague-Dawley rats.
por: Yager, J D
Publicado: (1983)

Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats
por: Xue, Li-Jun, et al.
Publicado: (2020)

The Addition of Liquid Fructose to a Western-Type Diet in LDL-R(−/−) Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge
por: Sangüesa, Gemma, et al.
Publicado: (2017)

Ovarian neoplasia in the Sprague-Dawley rat.
por: Lewis, D J
Publicado: (1987)

Hematoxicity of Amodiaquine in Sprague-Dawley Rats
por: Saka, W. A., et al.
Publicado: (2012)

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats
por: Kanitani, Masanao, et al.
Publicado: (2016)

Phyllanthus Niruri Standardized Extract Alleviates the Progression of Non-Alcoholic Fatty Liver Disease and Decreases Atherosclerotic Risk in Sprague–Dawley Rats
por: Al Zarzour, Raghdaa Hamdan, et al.
Publicado: (2017)

Brain, Liver, and Serum Salusin-alpha and -beta Alterations in Sprague-Dawley Rats with or without Metabolic Syndrome
por: Citil, Cihan, et al.
Publicado: (2014)

Development of a New Technique for Reconstruction of Hepatic Artery during Liver Transplantation in Sprague-Dawley Rat
por: Liu, Xingmu, et al.
Publicado: (2015)

Effects of Chitosan Oligosaccharide on Plasma and Hepatic Lipid Metabolism and Liver Histomorphology in Normal Sprague-Dawley Rats
por: Liu, Shing-Hwa, et al.
Publicado: (2020)

Prooxidation and Cytotoxicity of Selenium Nanoparticles at Nonlethal Level in Sprague-Dawley Rats and Buffalo Rat Liver Cells
por: Wang, Haidong, et al.
Publicado: (2020)

The effect of liver interference on mammary tumour induction by 7,12-dimethylbenz(a)anthracene in Sprague-Dawley rats.
por: Kernohan, I. R., et al.
Publicado: (1967)

Hepaprotective Effect of Standardized Ecklonia stolonifera Formulation on CCl(4)-Induced Liver Injury in Sprague-Dawley Rats
por: Byun, Jae-Hyuk, et al.
Publicado: (2018)

Effect of long-term administration of Cinnamomum cassia silver nanoparticles on organs (kidneys and liver) of Sprague-Dawley rats
por: KOUAME, Kofi, et al.
Publicado: (2018)

Hepatoprotective effects of methanolic extract of green tea against Thioacetamide-Induced liver injury in Sprague Dawley rats
por: Hamad Shareef, Suhayla, et al.
Publicado: (2022)

Cutaneous Hybrid Cyst in a Sprague-Dawley Rat
por: Yasuno, Kyohei, et al.
Publicado: (2012)

Intratubular Spermatocytic Seminomas in 2 Sprague-Dawley Rats
por: Ishigami, Noriaki, et al.
Publicado: (2014)

Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
por: Lim, Jeong-Hyeon, et al.
Publicado: (2010)

Splenic Hemangiosarcoma in a Young Sprague-Dawley Rat
por: Shiraki, Katsuhisa, et al.
Publicado: (2012)

Subchronic Inhalation Toxicity of Trichloroacetonitrile on the Sprague Dawley Rats
por: Han, Jeong-Hee, et al.
Publicado: (2015)

Memory deficits in Sprague Dawley rats with spontaneous ventriculomegaly
por: Luna‐Munguia, Hiram, et al.
Publicado: (2020)

Solitary foot mass on a Sprague-Dawley rat
por: Rosenbaum, Matthew D, et al.
Publicado: (2010)

Reproductive effects of sulfoxaflor in male Sprague Dawley rats
por: Mohamed, Wafaa H., et al.
Publicado: (2022)

Bempedoic acid for the treatment of dyslipidemia
por: Marrs, Joel C, et al.
Publicado: (2020)

Bempedoic Acid: for Whom and When
por: Ruscica, Massimiliano, et al.
Publicado: (2022)

Effects of taurine on plasma and liver lipids, erythrocyte ouabain sensitive Na efflux and platelet aggregation in Sprague Dawley rats
por: Park, In Sun, et al.
Publicado: (2007)

Histological study of smoke extract of Tobacco nicotiana on the heart, liver, lungs, kidney, and testes of male Sprague-Dawley rats
por: Adedayo, Adekomi Damilare, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_29lqsdthu2qlqdam8cmgu2m0cf