Cargando…

The Antineoplastic Effect of Carboplatin Is Potentiated by Combination with Pitavastatin or Metformin in a Chemoresistant High-Grade Serous Carcinoma Cell Line

The combination of Carboplatin with Paclitaxel is the mainstay treatment for high-grade serous carcinoma; however, many patients with advanced disease undergo relapse due to chemoresistance. Drug repurposing coupled with a combination of two or more compounds with independent mechanisms of action ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Nunes, Mariana, Duarte, Diana, Vale, Nuno, Ricardo, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820586/
https://www.ncbi.nlm.nih.gov/pubmed/36613537
http://dx.doi.org/10.3390/ijms24010097