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Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice

Amyotrophic Lateral Sclerosis (ALS) is a devastating adult-onset neurodegenerative disease, with ineffective therapeutic options. ALS incidence and prevalence depend on the sex of the patient. Histone deacetylase 4 (HDAC4) expression in skeletal muscle directly correlates with the progression of ALS...

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Detalles Bibliográficos
Autores principales:	Renzini, Alessandra, Pigna, Eva, Rocchi, Marco, Cedola, Alessia, Gigli, Giuseppe, Moresi, Viviana, Coletti, Dario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820722/ https://www.ncbi.nlm.nih.gov/pubmed/36613534 http://dx.doi.org/10.3390/ijms24010098

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