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Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading

Muscle unloading leads to signaling alterations that cause muscle atrophy and weakness. The cellular energy sensor AMPK can regulate myofiber-type shift, calcium-dependent signaling and ubiquitin-proteasome system markers. We hypothesized that the prevention of p-AMPK downregulation during the first...

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Detalles Bibliográficos
Autores principales:	Sharlo, Kristina A., Lvova, Irina D., Belova, Svetlana P., Zaripova, Ksenia A., Shenkman, Boris S., Nemirovskaya, Tatiana L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820761/ https://www.ncbi.nlm.nih.gov/pubmed/36613942 http://dx.doi.org/10.3390/ijms24010503

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