Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV(+) Interneurons, Synaptic Plasticity and Working Memory

Neonatal hypoxic-ischemic (HI) injury leads to deficits in hippocampal parvalbumin (PV)(+) interneurons (INs) and working memory. Therapeutic hypothermia (TH) does not prevent these deficits. ErbB4 supports maturation and maintenance of PV(+) IN. Thus, we hypothesized that neonatal HI leads to persi...

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Detalles Bibliográficos
Autores principales: Spahic, Harisa, Parmar, Pritika, Miller, Sarah, Emerson, Paul Casey, Lechner, Charles, St. Pierre, Mark, Rastogi, Neetika, Nugent, Michael, Duck, Sarah Ann, Kirkwood, Alfredo, Chavez-Valdez, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820818/
https://www.ncbi.nlm.nih.gov/pubmed/36613949
http://dx.doi.org/10.3390/ijms24010508

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