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Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears

Activating transcription factor 4 (ATF4) is involved in muscle atrophy through the overexpression of some atrogenes. However, it also controls the transcription of genes involved in muscle homeostasis maintenance. Here, we explored the effect of ATF4 activation by the pharmacological molecule halofu...

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Detalles Bibliográficos
Autores principales: Cussonneau, Laura, Coudy-Gandilhon, Cécile, Deval, Christiane, Chaouki, Ghita, Djelloul-Mazouz, Mehdi, Delorme, Yoann, Hermet, Julien, Gauquelin-Koch, Guillemette, Polge, Cécile, Taillandier, Daniel, Averous, Julien, Bruhat, Alain, Jousse, Céline, Papet, Isabelle, Bertile, Fabrice, Lefai, Etienne, Fafournoux, Pierre, Maurin, Anne-Catherine, Combaret, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820832/
https://www.ncbi.nlm.nih.gov/pubmed/36614063
http://dx.doi.org/10.3390/ijms24010621

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