Post-Cardiac Arrest: Mechanisms, Management, and Future Perspectives

Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to 22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest syndrome, which is characterized by the ischemia-reperfusion injury that affects the role body. Understanding p...

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Detalles Bibliográficos
Autores principales: Lazzarin, Taline, Tonon, Carolina Rodrigues, Martins, Danilo, Fávero, Edson Luiz, Baumgratz, Thiago Dias, Pereira, Filipe Welson Leal, Pinheiro, Victor Rocha, Ballarin, Raquel Simões, Queiroz, Diego Aparecido Rios, Azevedo, Paula Schmidt, Polegato, Bertha Furlan, Okoshi, Marina Politi, Zornoff, Leonardo, Rupp de Paiva, Sergio Alberto, Minicucci, Marcos Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820907/
https://www.ncbi.nlm.nih.gov/pubmed/36615059
http://dx.doi.org/10.3390/jcm12010259
Descripción
Sumario:Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to 22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest syndrome, which is characterized by the ischemia-reperfusion injury that affects the role body. Understanding physiopathology is mandatory to discover new treatment strategies and obtain better results. Besides improvements in cardiopulmonary resuscitation maneuvers, the great increase in survival rates observed in recent decades is due to new approaches to post-cardiac arrest care. In this review, we will discuss physiopathology, etiologies, and post-resuscitation care, emphasizing targeted temperature management, early coronary angiography, and rehabilitation.

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