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Innovative Anti-CD38 and Anti-BCMA Targeted Therapies in Multiple Myeloma: Mechanisms of Action and Resistance

CD38 and B-cell maturation antigens (BCMAs) are prevalently expressed on neoplastic plasma cells in multiple myeloma (MM), making them ideal therapeutic targets. Anti-CD38 monoclonal antibodies, such as approved daratumumab and isatuximab, are currently the milestone in MM treatment because they ind...

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Detalles Bibliográficos
Autores principales:	De Novellis, Danilo, Fontana, Raffaele, Giudice, Valentina, Serio, Bianca, Selleri, Carmine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820921/ https://www.ncbi.nlm.nih.gov/pubmed/36614086 http://dx.doi.org/10.3390/ijms24010645

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