A Comprehensive Assessment of Right Ventricular Function in Chronic Thromboembolic Pulmonary Hypertension

While chronic thromboembolic pulmonary hypertension (CTEPH) results from macroscopic and microscopic obstruction of the pulmonary vascular bed, the function of the right ventricle (RV) and increased RV afterload are the main determinants of its symptoms and prognosis. In this review, we assess RV fu...

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Detalles Bibliográficos
Autores principales: Marchetta, Stella, Verbelen, Tom, Claessen, Guido, Quarck, Rozenn, Delcroix, Marion, Godinas, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821031/
https://www.ncbi.nlm.nih.gov/pubmed/36614845
http://dx.doi.org/10.3390/jcm12010047
Descripción
Sumario:While chronic thromboembolic pulmonary hypertension (CTEPH) results from macroscopic and microscopic obstruction of the pulmonary vascular bed, the function of the right ventricle (RV) and increased RV afterload are the main determinants of its symptoms and prognosis. In this review, we assess RV function in patients diagnosed with CTEPH with a focus on the contributions of RV afterload and dysfunction to the pathogenesis of this disease. We will also discuss changes in RV function and geometry in response to treatment, including medical therapy, pulmonary endarterectomy, and balloon pulmonary angioplasty.

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