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Chromosomal Rearrangements and Chromothripsis: The Alternative End Generation Model

Chromothripsis defines a genetic phenomenon where up to hundreds of clustered chromosomal rearrangements can arise in a single catastrophic event. The phenomenon is associated with cancer and congenital diseases. Most current models on the origin of chromothripsis suggest that prior to chromatin res...

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Detalles Bibliográficos
Autores principales:	de Groot, Daniel, Spanjaard, Aldo, Hogenbirk, Marc A., Jacobs, Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821053/ https://www.ncbi.nlm.nih.gov/pubmed/36614236 http://dx.doi.org/10.3390/ijms24010794

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