Cargando…
High Acetate Concentration Protects Intestinal Barrier and Exerts Anti-Inflammatory Effects in Organoid-Derived Epithelial Monolayer Cultures from Patients with Ulcerative Colitis
Short-chain fatty acids as well as their bacterial producers are of increasing interest in inflammatory bowel diseases. Although less studied compared to butyrate, acetate might also be of interest as it may be less toxic to epithelial cells, stimulate butyrate-producing bacteria by cross-feeding, a...
Autores principales: | Deleu, Sara, Arnauts, Kaline, Deprez, Lowie, Machiels, Kathleen, Ferrante, Marc, Huys, Geert R. B., Thevelein, Johan M., Raes, Jeroen, Vermeire, Séverine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821118/ https://www.ncbi.nlm.nih.gov/pubmed/36614212 http://dx.doi.org/10.3390/ijms24010768 |
Ejemplares similares
-
Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis
por: Vancamelbeke, Maaike, et al.
Publicado: (2019) -
Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?
por: Deleu, Sara, et al.
Publicado: (2021) -
Organoid-based Models to Study the Role of Host-microbiota Interactions in IBD
por: Poletti, Martina, et al.
Publicado: (2020) -
Microbiota, not host origin drives ex vivo intestinal epithelial responses
por: Arnauts, Kaline, et al.
Publicado: (2022) -
Community Types of the Human Gut Virome are Associated with Endoscopic Outcome in Ulcerative Colitis
por: Jansen, Daan, et al.
Publicado: (2023)