Cargando…

Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study

The aim of this study was to examine the association between frailty risk and outcomes in older patients with pneumonia. For this purpose, the JMDC multi-center database was used, and a historical cohort study was conducted to examine the association between the Hospital Frailty Risk Score (HFRS) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Hori, Shinsuke, Yamamoto, Yoshinori, Ushida, Kenta, Shirai, Yuka, Shimizu, Miho, Kato, Yuki, Shimizu, Akio, Momosaki, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821132/
https://www.ncbi.nlm.nih.gov/pubmed/36614878
http://dx.doi.org/10.3390/jcm12010077
_version_ 1784865624619483136
author Hori, Shinsuke
Yamamoto, Yoshinori
Ushida, Kenta
Shirai, Yuka
Shimizu, Miho
Kato, Yuki
Shimizu, Akio
Momosaki, Ryo
author_facet Hori, Shinsuke
Yamamoto, Yoshinori
Ushida, Kenta
Shirai, Yuka
Shimizu, Miho
Kato, Yuki
Shimizu, Akio
Momosaki, Ryo
author_sort Hori, Shinsuke
collection PubMed
description The aim of this study was to examine the association between frailty risk and outcomes in older patients with pneumonia. For this purpose, the JMDC multi-center database was used, and a historical cohort study was conducted to examine the association between the Hospital Frailty Risk Score (HFRS) and oral intake prognosis and length of hospital stay in older patients hospitalized with pneumonia. Patients were classified into low-risk (HFRS < 5), intermediate-risk (HFRS = 5–15), and high-risk (HFRS > 15) groups based on their HFRS scores, and outcomes were defined as the number of days from admission to the start of oral intake and length of hospital stay. A total of 98,420 patients with pneumonia (mean age 82.2 ± 7.2) were finally included. Of these patients, 72,207 (73.4%) were in the low-risk group, 23,136 (23.5%) were in the intermediate-risk group, and 3077 (3.1%) were in the high-risk group. The intermediate- and high-risk groups had a higher number of days to the start of oral intake than the low-risk group (intermediate-risk group: coefficient 0.705, 95% confidence interval [CI] 0.642–0.769; high-risk group: coefficient 0.889, 95% CI 0.740–1.038). In addition, the intermediate- and high-risk groups also had longer hospital stays than the low-risk group (intermediate-risk group: coefficient 5.743, 95% CI 5.305–6.180; high-risk group: coefficient 7.738, 95% CI 6.709–8.766). Overall, we found that HFRS is associated with delayed initiation of oral intake and prolonged hospital stay in older patients with pneumonia. Therefore, evaluation based on HFRS could be helpful in making clinical decisions regarding the selection of feeding strategies and when to discharge older patients with pneumonia.
format Online
Article
Text
id pubmed-9821132
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-98211322023-01-07 Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study Hori, Shinsuke Yamamoto, Yoshinori Ushida, Kenta Shirai, Yuka Shimizu, Miho Kato, Yuki Shimizu, Akio Momosaki, Ryo J Clin Med Article The aim of this study was to examine the association between frailty risk and outcomes in older patients with pneumonia. For this purpose, the JMDC multi-center database was used, and a historical cohort study was conducted to examine the association between the Hospital Frailty Risk Score (HFRS) and oral intake prognosis and length of hospital stay in older patients hospitalized with pneumonia. Patients were classified into low-risk (HFRS < 5), intermediate-risk (HFRS = 5–15), and high-risk (HFRS > 15) groups based on their HFRS scores, and outcomes were defined as the number of days from admission to the start of oral intake and length of hospital stay. A total of 98,420 patients with pneumonia (mean age 82.2 ± 7.2) were finally included. Of these patients, 72,207 (73.4%) were in the low-risk group, 23,136 (23.5%) were in the intermediate-risk group, and 3077 (3.1%) were in the high-risk group. The intermediate- and high-risk groups had a higher number of days to the start of oral intake than the low-risk group (intermediate-risk group: coefficient 0.705, 95% confidence interval [CI] 0.642–0.769; high-risk group: coefficient 0.889, 95% CI 0.740–1.038). In addition, the intermediate- and high-risk groups also had longer hospital stays than the low-risk group (intermediate-risk group: coefficient 5.743, 95% CI 5.305–6.180; high-risk group: coefficient 7.738, 95% CI 6.709–8.766). Overall, we found that HFRS is associated with delayed initiation of oral intake and prolonged hospital stay in older patients with pneumonia. Therefore, evaluation based on HFRS could be helpful in making clinical decisions regarding the selection of feeding strategies and when to discharge older patients with pneumonia. MDPI 2022-12-22 /pmc/articles/PMC9821132/ /pubmed/36614878 http://dx.doi.org/10.3390/jcm12010077 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hori, Shinsuke
Yamamoto, Yoshinori
Ushida, Kenta
Shirai, Yuka
Shimizu, Miho
Kato, Yuki
Shimizu, Akio
Momosaki, Ryo
Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title_full Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title_fullStr Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title_full_unstemmed Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title_short Impact of Frailty Risk on Oral Intake and Length of Hospital Stay in Older Patients with Pneumonia: A Historical Cohort Study
title_sort impact of frailty risk on oral intake and length of hospital stay in older patients with pneumonia: a historical cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821132/
https://www.ncbi.nlm.nih.gov/pubmed/36614878
http://dx.doi.org/10.3390/jcm12010077
work_keys_str_mv AT horishinsuke impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT yamamotoyoshinori impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT ushidakenta impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT shiraiyuka impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT shimizumiho impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT katoyuki impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT shimizuakio impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy
AT momosakiryo impactoffrailtyriskonoralintakeandlengthofhospitalstayinolderpatientswithpneumoniaahistoricalcohortstudy