Synthesis and Anticancer Evaluation of New Indole-Based Tyrphostin Derivatives and Their (p-Cymene)dichloridoruthenium(II) Complexes

New N-alkylindole-substituted 2-(pyrid-3-yl)-acrylonitriles with putative kinase inhibitory activity and their (p-cymene)Ru(II) piano-stool complexes were prepared and tested for their antiproliferative efficacy in various cancer models. Some of the indole-based derivatives inhibited tumor cell prol...

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Detalles Bibliográficos
Autores principales: Oberhuber, Natalie, Ghosh, Hindole, Nitzsche, Bianca, Dandawate, Prasad, Höpfner, Michael, Schobert, Rainer, Biersack, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821196/
https://www.ncbi.nlm.nih.gov/pubmed/36614289
http://dx.doi.org/10.3390/ijms24010854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821196/
https://www.ncbi.nlm.nih.gov/pubmed/36614289
http://dx.doi.org/10.3390/ijms24010854

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