A high-throughput single-particle imaging platform for antibody characterization and a novel competition assay for therapeutic antibodies

Monoclonal antibodies (mAbs) play an important role in diagnostics and therapy of infectious diseases. Here we utilize a single-particle interferometric reflectance imaging sensor (SP-IRIS) for screening 30 mAbs against Ebola, Sudan, and Lassa viruses (EBOV, SUDV, and LASV) to find out the ideal cap...

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Detalles Bibliográficos
Autores principales: Seymour, Elif, Ünlü, M. Selim, Connor, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821353/
https://www.ncbi.nlm.nih.gov/pubmed/36609657
http://dx.doi.org/10.1038/s41598-022-27281-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821353/
https://www.ncbi.nlm.nih.gov/pubmed/36609657
http://dx.doi.org/10.1038/s41598-022-27281-w

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