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The Management of Ocular Surface Squamous Neoplasia (OSSN)
The rise of primary topical monotherapy with chemotherapeutic drugs and immunomodulatory agents represents an increasing recognition of the medical management of ocular surface squamous neoplasia (OSSN), which may replace surgery as the standard of care in the future. Currently, there is no consensu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821412/ https://www.ncbi.nlm.nih.gov/pubmed/36614155 http://dx.doi.org/10.3390/ijms24010713 |
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author | Yeoh, Clarice H. Y. Lee, Jerome J. R. Lim, Blanche X. H. Sundar, Gangadhara Mehta, Jodhbir S. Chan, Anita S. Y. Lim, Dawn K. A. Watson, Stephanie L. Honavar, Santosh G. Manotosh, Ray Lim, Chris H. L. |
author_facet | Yeoh, Clarice H. Y. Lee, Jerome J. R. Lim, Blanche X. H. Sundar, Gangadhara Mehta, Jodhbir S. Chan, Anita S. Y. Lim, Dawn K. A. Watson, Stephanie L. Honavar, Santosh G. Manotosh, Ray Lim, Chris H. L. |
author_sort | Yeoh, Clarice H. Y. |
collection | PubMed |
description | The rise of primary topical monotherapy with chemotherapeutic drugs and immunomodulatory agents represents an increasing recognition of the medical management of ocular surface squamous neoplasia (OSSN), which may replace surgery as the standard of care in the future. Currently, there is no consensus regarding the best way to manage OSSN with no existing guidelines to date. This paper seeks to evaluate evidence surrounding available treatment modalities and proposes an approach to management. The approach will guide ophthalmologists in selecting the most appropriate treatment regime based on patient and disease factors to minimize treatment related morbidity and improve OSSN control. Further work can be done to validate this algorithm and to develop formal guidelines to direct the management of OSSN. |
format | Online Article Text |
id | pubmed-9821412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98214122023-01-07 The Management of Ocular Surface Squamous Neoplasia (OSSN) Yeoh, Clarice H. Y. Lee, Jerome J. R. Lim, Blanche X. H. Sundar, Gangadhara Mehta, Jodhbir S. Chan, Anita S. Y. Lim, Dawn K. A. Watson, Stephanie L. Honavar, Santosh G. Manotosh, Ray Lim, Chris H. L. Int J Mol Sci Review The rise of primary topical monotherapy with chemotherapeutic drugs and immunomodulatory agents represents an increasing recognition of the medical management of ocular surface squamous neoplasia (OSSN), which may replace surgery as the standard of care in the future. Currently, there is no consensus regarding the best way to manage OSSN with no existing guidelines to date. This paper seeks to evaluate evidence surrounding available treatment modalities and proposes an approach to management. The approach will guide ophthalmologists in selecting the most appropriate treatment regime based on patient and disease factors to minimize treatment related morbidity and improve OSSN control. Further work can be done to validate this algorithm and to develop formal guidelines to direct the management of OSSN. MDPI 2022-12-31 /pmc/articles/PMC9821412/ /pubmed/36614155 http://dx.doi.org/10.3390/ijms24010713 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yeoh, Clarice H. Y. Lee, Jerome J. R. Lim, Blanche X. H. Sundar, Gangadhara Mehta, Jodhbir S. Chan, Anita S. Y. Lim, Dawn K. A. Watson, Stephanie L. Honavar, Santosh G. Manotosh, Ray Lim, Chris H. L. The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title | The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title_full | The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title_fullStr | The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title_full_unstemmed | The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title_short | The Management of Ocular Surface Squamous Neoplasia (OSSN) |
title_sort | management of ocular surface squamous neoplasia (ossn) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821412/ https://www.ncbi.nlm.nih.gov/pubmed/36614155 http://dx.doi.org/10.3390/ijms24010713 |
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