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β-patchoulene alleviates cognitive dysfunction in a mouse model of sepsis associated encephalopathy by inhibition of microglia activation through Sirt1/Nrf2 signaling pathway

BACKGROUND: Sepsis associated encephalopathy (SAE) is a common but poorly understood complication during sepsis. Currently, there are no preventive or therapeutic agents available for this neurological disorder. The present study was designed to determine the potential protective effects of β-patcho...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Wang, Lin, Fan, Xiaojing, Zhang, Hui, Dong, Zhiwei, Tao, Tianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821490/
https://www.ncbi.nlm.nih.gov/pubmed/36608000
http://dx.doi.org/10.1371/journal.pone.0279964