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Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study

Purpose: Surgical treatment is an important part of the management of Crohn’s disease (CD). However, the current recommended staged procedures require two operations, with long hospital stays and high costs, while traditional primary anastomosis has a high risk of complications. Therefore, the aim o...

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Autores principales: Deng, Aojian, Zheng, Shaopeng, Yuan, Lianwen, Xiang, Kaimin, Wang, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821564/
https://www.ncbi.nlm.nih.gov/pubmed/36615164
http://dx.doi.org/10.3390/jcm12010364
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author Deng, Aojian
Zheng, Shaopeng
Yuan, Lianwen
Xiang, Kaimin
Wang, Fen
author_facet Deng, Aojian
Zheng, Shaopeng
Yuan, Lianwen
Xiang, Kaimin
Wang, Fen
author_sort Deng, Aojian
collection PubMed
description Purpose: Surgical treatment is an important part of the management of Crohn’s disease (CD). However, the current recommended staged procedures require two operations, with long hospital stays and high costs, while traditional primary anastomosis has a high risk of complications. Therefore, the aim of this study was to compare the clinical efficacy and safety of modified primary anastomosis using intestinal internal drainage tubes for CD. Methods: In this study, emergency and nonemergency CD patients were included separately. Then, the patients were divided into three subgroups: patients with intestinal internal drainage tubes (modified primary anastomosis), staged procedures, and traditional primary anastomosis. The main outcomes were the number of hospitalizations, length and cost of the first hospital stay, length and cost of total hospital stays, and complications. Results: The outcomes of the three subgroups of emergency CD patients were not significantly different. For nonemergency CD patients, patients with intestinal internal drainage tubes had shorter total hospital stays and fewer hospitalizations compared with the staged procedures subgroup, while no significant differences in any outcomes were observed between the modified and traditional primary anastomosis subgroups. Conclusions: For emergency CD patients, no significant advantage in terms of the main outcomes was observed for modified primary anastomosis. For nonemergency CD patients, modified primary anastomosis reduced the length of total hospital stays and hospitalizations compared with staged procedures. The placement of intestinal internal drainage tubes allows some patients who cannot undergo primary anastomosis to undergo it, which is a modification of traditional primary anastomosis.
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spelling pubmed-98215642023-01-07 Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study Deng, Aojian Zheng, Shaopeng Yuan, Lianwen Xiang, Kaimin Wang, Fen J Clin Med Article Purpose: Surgical treatment is an important part of the management of Crohn’s disease (CD). However, the current recommended staged procedures require two operations, with long hospital stays and high costs, while traditional primary anastomosis has a high risk of complications. Therefore, the aim of this study was to compare the clinical efficacy and safety of modified primary anastomosis using intestinal internal drainage tubes for CD. Methods: In this study, emergency and nonemergency CD patients were included separately. Then, the patients were divided into three subgroups: patients with intestinal internal drainage tubes (modified primary anastomosis), staged procedures, and traditional primary anastomosis. The main outcomes were the number of hospitalizations, length and cost of the first hospital stay, length and cost of total hospital stays, and complications. Results: The outcomes of the three subgroups of emergency CD patients were not significantly different. For nonemergency CD patients, patients with intestinal internal drainage tubes had shorter total hospital stays and fewer hospitalizations compared with the staged procedures subgroup, while no significant differences in any outcomes were observed between the modified and traditional primary anastomosis subgroups. Conclusions: For emergency CD patients, no significant advantage in terms of the main outcomes was observed for modified primary anastomosis. For nonemergency CD patients, modified primary anastomosis reduced the length of total hospital stays and hospitalizations compared with staged procedures. The placement of intestinal internal drainage tubes allows some patients who cannot undergo primary anastomosis to undergo it, which is a modification of traditional primary anastomosis. MDPI 2023-01-03 /pmc/articles/PMC9821564/ /pubmed/36615164 http://dx.doi.org/10.3390/jcm12010364 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Deng, Aojian
Zheng, Shaopeng
Yuan, Lianwen
Xiang, Kaimin
Wang, Fen
Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title_full Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title_fullStr Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title_full_unstemmed Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title_short Modified Primary Anastomosis Using an Intestinal Internal Drainage Tube for Crohn’s Disease: A Pilot Study
title_sort modified primary anastomosis using an intestinal internal drainage tube for crohn’s disease: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821564/
https://www.ncbi.nlm.nih.gov/pubmed/36615164
http://dx.doi.org/10.3390/jcm12010364
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