Disulfiram Ophthalmic Solution Inhibited Macrophage Infiltration by Suppressing Macrophage Pseudopodia Formation in a Rat Corneal Alkali Burn Model

FROUNT is an intracellular protein that promotes pseudopodia formation by binding to the chemokine receptors CCR2 and CCR5 on macrophages. Recently, disulfiram (DSF), a drug treatment for alcoholism, was found to have FROUNT inhibitory activity. In this study, we investigated the effect of DSF eye d...

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Detalles Bibliográficos
Autores principales: Ikebukuro, Toyo, Arima, Takeshi, Kasamatsu, Momoko, Nakano, Yuji, Tobita, Yutaro, Uchiyama, Masaaki, Terashima, Yuya, Toda, Etsuko, Shimizu, Akira, Takahashi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821574/
https://www.ncbi.nlm.nih.gov/pubmed/36614177
http://dx.doi.org/10.3390/ijms24010735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821574/
https://www.ncbi.nlm.nih.gov/pubmed/36614177
http://dx.doi.org/10.3390/ijms24010735

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