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Effect of Ionization Degree of Poly(amidoamine) Dendrimer and 5-Fluorouracil on the Efficiency of Complex Formation—A Theoretical and Experimental Approach
Due to their unique structure, poly(amidoamine) (PAMAM) dendrimers can bind active ingredients in two ways: inside the structure or on their surface. The location of drug molecules significantly impacts the kinetics of active substance release and the mechanism of internalization into the cell. This...
Autores principales: | Szota, Magdalena, Wolski, Pawel, Carucci, Cristina, Marincola, Flaminia Cesare, Gurgul, Jacek, Panczyk, Tomasz, Salis, Andrea, Jachimska, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821593/ https://www.ncbi.nlm.nih.gov/pubmed/36614260 http://dx.doi.org/10.3390/ijms24010819 |
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