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Effect of Ionization Degree of Poly(amidoamine) Dendrimer and 5-Fluorouracil on the Efficiency of Complex Formation—A Theoretical and Experimental Approach

Due to their unique structure, poly(amidoamine) (PAMAM) dendrimers can bind active ingredients in two ways: inside the structure or on their surface. The location of drug molecules significantly impacts the kinetics of active substance release and the mechanism of internalization into the cell. This...

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Detalles Bibliográficos
Autores principales: Szota, Magdalena, Wolski, Pawel, Carucci, Cristina, Marincola, Flaminia Cesare, Gurgul, Jacek, Panczyk, Tomasz, Salis, Andrea, Jachimska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821593/
https://www.ncbi.nlm.nih.gov/pubmed/36614260
http://dx.doi.org/10.3390/ijms24010819

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